A Breakthrough in Veterinary Medicine
The Future of Pain-Free Living
Autologous Conditioned Serum (ACS)
Discover the groundbreaking Autologous Conditioned Serum (ACS) therapy and the Orthogen® Vet Device. Our game-changer in treating dog osteoarthritis and synovitis. Join our mission to provide long-term pain relief and improved quality of life for dogs. Learn how ACS therapy can transform your practice and help dogs live happier, healthier lives.
As a K9 unit handler, my dog is my partner and when he developed synovitis, I was terrified. This treatment reduced his pain and also improved his mobility significantly.
Officer Mark R.
My 10-year-old Labrador, Max, was struggling with severe hip osteoarthritis. He could barely walk, and it broke my heart to see him in so much pain. Within weeks, Max was moving around like a puppy again. Thank you!
Sarah T.
I was hesitant about intra-articular injections for my little Bella. It was quick, and Bella showed improvement within days. I’m so grateful for making this possible.
James P.
Our German Shepherd, Luna, who has chronic joint inflammation—medications, supplements, even physical therapy. Nothing worked long-term until we found ACS therapy. Luna is more active, playful, and pain-free. Truthfully, a miracle.
Emily L.
A new treatment is significantly more effective in improving symptoms of moderate to severe hip osteoarthritis in dogs than glucocorticoid alone, according a study published this week in “Advances in Diagnostic and Treatment Methods for Joint Diseases in Dogs and Cats,” a special issue published by the veterinary journal Animals.
Trial results show that one intra-articular shot of autologous conditioned serum (ACS) improves the overall health of dogs with osteoarthritis and that the combination of ACS with the glucocorticoid triamcinolone led to even faster and longer-lasting improvements in function and pain. Adult dogs with osteoarthritis in their hips suffer severe pain and limited movement, lowering their quality of life.
The study compared treatment with ACS alone, treatment with glucocorticoids alone (in the previously published* first arm of the cross over) and treatment with ORTHOGEN AG’s patented therapy of concomitant ACS and glucocorticoids.
ACS contains the entire blood cell secretome (BCS) after extended coagulation in a defined environment. It contains anti-inflammatory and anabolic proteins derived from the dog’s own blood and is processed using Orthogen Veterinary’s newly-developed proprietary device (OrthogenDevice vet).
“I have studied multiple autologous blood products and other intra-articular treatments, and Orthogen’s approach was a very effective treatment, with surprisingly sustainable results,” says Dr. Joao Alves, a veterinarian and the study’s lead author. Dr. Alves also is a police captain who specialises in intra-articular treatments for osteoarthritis in highly trained police working dogs.
A Comparison of Intra-Articular Blood Cell Secretome and Blood Cell Secretome with Triamcinolone Acetonide in Dogs with Osteoarthritis: A Crossover Study
Animals 2022, 12(23), 3358; https://doi.org/10.3390/ani12233358 – 30 Nov 2022
*Alves JC, Santos A, Jorge P, Carreira LM. A first report on the efficacy of a single intra-articular administration of blood cell secretome, triamcinolone acetonide, and the combination of both in dogs with osteoarthritis. BMC Vet Res. Published online 2022:1-10. doi:10.1186/s12917-022-03413-2
ACS therapy is a cutting-edge treatment for dogs suffering from osteoarthritis and synovitis. It involves using the Orthogen® Device to stimulate the dog’s own blood cells to produce beneficial proteins and anti-inflammatory factors. The resulting serum is then injected into the affected joint to reduce pain, inflammation, and promote healing.
The Orthogen® Device creates a controlled environment to stimulate the dog’s venous blood extracorporeally (outside the body). This process encourages the blood cells to produce healing proteins and anti-inflammatory factors. The resulting ACS is a sterile, cell-free solution that is injected into the affected joint to provide long-term pain relief and improved mobility.
Yes, ACS therapy is safe. The serum is derived from your dog’s own blood, reducing the risk of adverse reactions. It is also sterile-filtered, minimizing contamination risks. Clinical studies have shown that ACS therapy is well-tolerated and effective for dogs with joint conditions.
ACS therapy is primarily used to treat:
Osteoarthritis (OA)
Synovitis (joint inflammation)
Chronic or acute joint inflammation
Post-operative care following joint surgery
Many dogs show improvement within a few weeks of treatment. ACS therapy provides both early pain relief and long-term benefits, with some dogs experiencing improved mobility and quality of life for months after treatment.
The number of treatments depends on the severity of the condition and the dog’s response to therapy. Your veterinarian will create a customized treatment plan, which may include multiple injections over several weeks.
Yes, ACS therapy can be combined with other treatments, such as glucocorticoids (e.g., Triamcinolone) or physical therapy, to enhance results. Your veterinarian will determine the best approach for your dog’s specific needs.
ACS therapy is suitable for most dogs suffering from osteoarthritis or synovitis. However, your veterinarian will evaluate your dog’s health and medical history to ensure it’s the right treatment option.
The Orthogen® Device is used by veterinarians to process the dog’s blood and create ACS. The process is simple and standardized, ensuring consistent results. Veterinarians receive training to use the device effectively.
ACS therapy is generally well-tolerated, with minimal side effects. Some dogs may experience mild swelling or discomfort at the injection site, but these symptoms typically resolve quickly.
The cost of ACS therapy varies depending on the number of treatments and the veterinary clinic. Contact your veterinarian for specific pricing details.
Use our Locations tool to locate a clinic near you that offers ACS therapy and the Orthogen® Device. If your veterinarian isn’t yet familiar with ACS therapy, encourage them to contact us for more information.
While ACS therapy is primarily designed for dogs, it has shown promise in treating joint conditions in other animals, such as horses and cats. Consult your veterinarian for more information.
Your veterinarian will provide specific instructions, but generally, no special preparation is needed. Ensure your dog is healthy and up-to-date on vaccinations before treatment.
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